Developing Insights in Cartilage Repair

Developing Insights in Cartilage Repair

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This comprehensive book discusses cartilage repair and all its aspects. These aspects vary from basic insights in cartilage biology and regeneration via MRI, to results of existing cartilage repair techniques and upcoming novel approaches. Fundamental cartilage biology is the topic covered within the first chapters of the book. These chapters not only provide an insight in healthy, damaged and regenerative cartilage but also describe developments in gene therapy and methods to enhance chondrogenesis of stemcells and prevent hypertophic differentiation. There is a huge progress in the possibilities of MR imaging of both healthy, damaged and regenerative cartilage. These developments not only enable better monitoring of cartilage repair but may also unravel the pathophysiology of the development of cartilage defects. Different cartilage repair techniques (e.g. allografts, autologous chondrocytes transplantation [ACT], microfracture), there technical aspects (e.g. developments towards an total arthroscopic approach), pitfalls, and outcomes are reported in the following chapters. In these chapters factors important for the results of cartilage repair such as meniscal repair, patient factors are described. Finally, an overview of novel cartilage repair techniques such as minced cartilage, denovo cartilage and more areas are discussed in this comprehensive addition to the of focal patellar defects were reported by transplantation of cultured autologous cells in the rabbit [7, 8]. ... Della#39;Accio et al. conducted basic research on mesenchymal cell populationsa#39; ability to form stable cartilage in vivo in the nude, i.e. immune suppressed, mouse, allowing to study human cell ... The Ectopic Cartilage Formation Assay (ECFA) was developed, allowing to test and monitor potencyanbsp;...

Title:Developing Insights in Cartilage Repair
Author: Pieter J. Emans, Lars Peterson
Publisher:Springer Science & Business Media - 2013-10-16

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